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A Predictive Nomogram for Predicting Improved Clinical Outcome Probability in Patients with COVID-19 Article

Jiaojiao Xie, Ding Shi, Mingyang Bao, Xiaoyi Hu, Wenrui Wu, Jifang Sheng, Kaijin Xu, Qing Wang, Jingjing Wu, Kaicen Wang, Daiqiong Fang, Yating Li, Lanjuan Li

Engineering 2022, Volume 8, Issue 1,   Pages 122-129 doi: 10.1016/j.eng.2020.05.014

Abstract: The nomogram we constructed is useful for clinicians to predict improved clinical outcome probabilityfor each COVID-19 patient, which may facilitate personalized counselling and treatment.

Keywords： Coronavirus disease 2019 (COVID-19)     Nomogram     Patient-relevant outcome    

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Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Frontiers of Engineering Management 2015, Volume 2, Issue 1,   Pages 2-12 doi: 10.15302/J-FEM-2015002

Abstract: following recommendations as strategies for chronic disease prevention and control and development of relevantAll relevant government departments should formulate corresponding policies; establish a coordinated

Keywords： chronic disease prevention and control     strategy and system construction    

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Fertility outcome analysis after modified laparoscopic microsurgical tubal anastomosis

Jihui Ai, Pei Zhang, Lei Jin, Yufeng Li, Jing Yue, Ding Ma, Hanwang Zhang

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 310-314 doi: 10.1007/s11684-011-0152-8

Abstract: The current study aims to evaluate the fertility outcome after modified laparoscopic microsurgical tubalunderwent modified laparoscopic microsurgical tubal anastomosis were monitored to investigate the fertility outcome

Keywords： modified laparoscopy     tubal anastomosis     microsurgery    

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Research on the relationship between Hengsha land formation and development and relevant planning

Ruan Wei,Lou Fei

Strategic Study of CAE 2013, Volume 15, Issue 6,   Pages 79-85

Abstract:

In this paper, on the basis of natural river regime evolution and relevant

Keywords： Yangtze river estuary     Hengsha     land formation and development     relevant planning    

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Arsenic trioxide induced rhabdomyolysis, a rare but severe side effect, in an APL patient: a case report

Haiyan He, Ran An, Jian Hou, Weijun Fu

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 284-286 doi: 10.1007/s11684-017-0514-y

Abstract: In this report, we present a rare side effect, rhabdomyolysis, in a 68-year-old female APL patient who

Keywords： arsenic trioxide     APL     rhabdomyolysis    

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FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 295-305 doi: 10.1007/s11684-021-0857-2

Abstract: tertile of plasma TMAO was associated with a significant increment in hazard ratio (HR) for the composite outcomeThus, higher plasma TMAO levels indicated increased risk of the composite outcome of cardiovascular death

Keywords： chronic heart failure     trimethylamine-N-oxide     flavin monooxygenase 3     single nucleotide polymorphism    

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Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research

Shuyang Sun,Zhiyuan Zhang

Frontiers of Medicine 2016, Volume 10, Issue 1,   Pages 104-110 doi: 10.1007/s11684-016-0432-4

Abstract: Patient-derived xenograft (PDX) models generated from human tumor samples that can retain the histologicalthe translational value of this well-annotated PDX panel in the development of co-clinical trials for patient

Keywords： patient-derived xenograft models     personalized medicine     co-clinical trial     patient stratification     oral    

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Easy access to pharmaceutically relevant heterocycles by catalytic reactions involving

Ximei Zhao, Matthias Rudolph, Abdullah M. Asiri, A. Stephen K. Hashmi

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 317-349 doi: 10.1007/s11705-019-1874-4

Abstract: This review summarizes recent advances in the field of gold-catalyzed synthesis of pharmaceutically relevant

Keywords： gold     heterocycles     alkynes    

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An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 506-509 doi: 10.1007/s11684-013-0294-y

Abstract:

This study aimed to investigate patient dose in diagnostic screen-film radiographic examinations in

Keywords： radiation dosage     radiology     radiation protection     radiography/statistics & numerical data    

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Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 150-155 doi: 10.1007/s11684-021-0846-5

Abstract: To identify the potential pathogenic mutations in a Chinese patient with CF, we conducted Sanger sequencingon the genomic DNA of the patient and his parents and detected all 27 coding exons of CFTR andThe patient is a compound heterozygote of c.2909G>A, p.Gly970Asp in exon 18 and c.1210-3C>G in cisOverall, c.1210-3C>G, the newly identified pathogenic mutation in our patient, in combination with T5Moreover, this patient carries a p.Gly970Asp mutation, thus confirming the high-frequency of this mutation

Keywords： cystic fibrosis     CFTR     splicing mutation     minigene    

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Innate immune checkpoint Siglec10 in cancers: mining of comprehensive omics data and validation in patient

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 596-609 doi: 10.1007/s11684-021-0868-z

Abstract: Sialic acid binding Ig-like lectin 10 (Siglec10) is a member of innate immune checkpoints that inhibits the activation of immune cells through the interaction with its ligand CD24 on tumor cells. Here, by analyzing public databases containing 64 517 patients of 33 cancer types, we found that the expression of Siglec10 was altered in 18 types of cancers and was associated with the clinical outcomes of 11 cancer types. In particular, Siglec10 was upregulated in patients with kidney renal clear cell carcinoma (KIRC) and was inversely associated with the prognosis of the patients. In 131 KIRC patients of our settings, Siglec10 was elevated in the tumor tissues of 83 (63.4%) patients compared with that in their counterpart normal kidney tissues. Moreover, higher level of Siglec10 was associated with advanced disease (stages III and IV) and worse prognosis. Silencing of CD24 in KIRC cells significantly increased the number of Siglec10-expressing macrophages phagocytosing KIRC cells. In addition, luciferase activity assays suggested that Siglec10 was a potential target of the transcription factors c-FOS and GATA1, which were identified by data mining. These results demonstrate that Siglec10 may have important oncogenic functions in KIRC, and represents a novel target for the development of immunotherapies.

Keywords： innate immune checkpoint     Siglec10     kidney renal clear cell carcinoma    

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Economy-oriented strategy of appropriate technique

CHEN Xiaoyang, ZHONG Dekun

Frontiers of Structural and Civil Engineering 2008, Volume 2, Issue 4,   Pages 371-378 doi: 10.1007/s11709-008-0047-1

Abstract: In light of the current situation of domestic technique and the relevant living example, it proposes

Keywords： outlook     relevant     appropriate technique     innovation     situation    

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Xingnao Kaiqiao acupuncture combined with Angong Niuhuang Wan for a patient under persistent vegetative

Hujie Song, Xiao Chen, Yalan Yu, Ling Zhang

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 334-339 doi: 10.1007/s11684-017-0539-2

Abstract: Our patient is a male and 5 years and 3 months of age.

Keywords： PVS     stubborn disease     Xingnao Kaiqiao     Angong Niuhuang Wan     TCM     acupuncture    

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Ventricular tachycardia in a disseminated MDR-TB patient: a case report and brief review of literature

Hui Li,Ran Li,Jiuxin Qu,Xiaomin Yu,Zhixin Cao,Yingmei Liu,Bin Cao

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 259-263 doi: 10.1007/s11684-014-0321-7

Abstract:

Although significant breakthroughs have been achieved in tuberculosis management, we still encounter numerous difficulties in diagnosis and treatment of the disease. Additionally, a new challenge, multidrug-resistant tuberculosis (MDR-TB) with unspecific clinical presentation, often results in delayed diagnosis. In this paper, we reported a case of disseminated tuberculosis with rare presentation of ventricular fibrillation, which proved resistant to both isoniazid and rifampicin. A review of literature showed that ventricular fibrillation or tachycardia in tuberculosis patients with pericarditis or myocarditis has been sporadically reported in the past, but none has been conducted involving patients with MDR-TB infections.

Keywords： tuberculosis     MDR-TB     ventricular tachycardia    

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Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Frontiers of Medicine 2014, Volume 8, Issue 2,   Pages 250-253 doi: 10.1007/s11684-014-0333-3

Abstract:

The clinical data of a patient with acute-on-chronic liver failure were analyzed retrospectively.The patient has suffered from hepatitis B for 30 years.The patient also presented hepatocellular carcinoma.The patient recovered uneventfully and was discharged after surgery.

Keywords： acute-on-chronic liver failure     submassive necrosis     viral hepatitis B     esophageal variceal bleeding     liver transplantation    

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Title Author Date Type Operation

A Predictive Nomogram for Predicting Improved Clinical Outcome Probability in Patients with COVID-19

Jiaojiao Xie, Ding Shi, Mingyang Bao, Xiaoyi Hu, Wenrui Wu, Jifang Sheng, Kaijin Xu, Qing Wang, Jingjing Wu, Kaicen Wang, Daiqiong Fang, Yating Li, Lanjuan Li

Journal Article

Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development

Long-de Wang

Journal Article

Fertility outcome analysis after modified laparoscopic microsurgical tubal anastomosis

Jihui Ai, Pei Zhang, Lei Jin, Yufeng Li, Jing Yue, Ding Ma, Hanwang Zhang

Journal Article

Research on the relationship between Hengsha land formation and development and relevant planning

Ruan Wei,Lou Fei

Journal Article

Arsenic trioxide induced rhabdomyolysis, a rare but severe side effect, in an APL patient: a case report

Haiyan He, Ran An, Jian Hou, Weijun Fu

Journal Article

FMO3--TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection

Journal Article

Patient-derived xenograft platform of OSCC: a renewable human bio-bank for preclinical cancer research

Shuyang Sun,Zhiyuan Zhang

Journal Article

Easy access to pharmaceutically relevant heterocycles by catalytic reactions involving

Ximei Zhao, Matthias Rudolph, Abdullah M. Asiri, A. Stephen K. Hashmi

Journal Article

An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Journal Article

Novel mutation c.1210-3C>G in with a poly-T tract of 5T affects mRNA splicing in a Chinese patient

Journal Article

Innate immune checkpoint Siglec10 in cancers: mining of comprehensive omics data and validation in patient

Journal Article

Economy-oriented strategy of appropriate technique

CHEN Xiaoyang, ZHONG Dekun

Journal Article

Xingnao Kaiqiao acupuncture combined with Angong Niuhuang Wan for a patient under persistent vegetative

Hujie Song, Xiao Chen, Yalan Yu, Ling Zhang

Journal Article

Ventricular tachycardia in a disseminated MDR-TB patient: a case report and brief review of literature

Hui Li,Ran Li,Jiuxin Qu,Xiaomin Yu,Zhixin Cao,Yingmei Liu,Bin Cao

Journal Article

Comprehensive treatment of acute-on-chronic liver failure in a patient with hepatitis B: a case report

Lei Li,Yimei Liu,Tiancheng Luo,Jian Zhou,Yingyong Hou,Xizhong Shen,Jiyao Wang

Journal Article